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Pradeep Luther - Selected Publications
Luther, P.K. and Squire, J.M. (1978) "Three-dimensional structure of the vertebrate muscle M-region" J.Mol.Biol. 125, 313-324.
Luther, P.K. and Squire, J.M. (1980) "Three-dimensional structure of the vertebrate muscle A-band. II. The myosin filament superlattice" J.Mol.Biol. 141, 409-439.
Luther, P.K., Munro, P.M.G. and Squire, J.M. (1981) "Three-dimensional structure of the vertebrate muscle A-band. III. M-region structure and myosin filament symmetry" J.Mol.Biol. 151, 703-730.
Luther, P.K. & Crowther, R.A. (1984) "Three-dimensional reconstruction from tilted sections of fish muscle M-band" Nature 307, 566-568.
Crowther, R.A. and Luther, P.K. (1984) "Three-dimensional reconstruction from a single oblique section of fish muscle M-band" Nature 307, 569-570.
Luther, P.K., Lawrence, M. and Crowther, R.A. (1988) "A method for monitoring the collapse of plastic sections in the electron microscope" Ultramicroscopy 24, 7-18. (Cover picture)
Luther, P.K. "Three-dimensional reconstruction of a simple Z-band in fish muscle" (1991) J. Cell Biol. 113, 1043-1055. (Cover picture)
Luther, P.K. Munro, P.M.G. & Squire, J.M. (1995) "Muscle ultrastructure in the teleost fish". Micron, 26, 431-459.
Luther, P.K. "Symmetry of vertebrate muscle basketweave Z-band", (1995) J. Structural Biology, 115, 275-282.
Luther, P.K., Squire, J.M. & Forey, P.L. (1996) "Evolution of the simple lattice and superlattice A-band in vertebrate skeletal muscle", Journal of Morphology 229, 329-335. (Chart)
Luther, P.K. (2000) Three-dimensional structure of a vertebrate muscle Z-band: Implications for titin and a -actinin binding. J. Struct. Biol., 129:1-16.
Luther, P.K., Barry, J. & Squire, J.M. (2002) Three-dimensional structure of a vertebrate wide (slow muscle) Z-band: Lessons on Z-band assembly. J. Mol. Biol. 315:9-19. (Journal Cover)
Luther, P.K. & Squire, J.M. (2002) Muscle Z-band ultrastructure: Titin Z-repeats and Z-band periodicities do not match. J. Mol. Biol. 319:1157-1164.
C.Knupp, P.K. Luther & J.M. Squire (2002) Titin organisation and the 3D architecture of the vertebrate striated muscle I-band. J. Mol. Biol. 322:731-739. (Journal Cover)
Luther, P.K. & Morris, E.P. (2003) Cryo-electron microscopy of refrozen cryosections. J. Struct. Biol. 142:233-240.
J.M. Squire, P.K. Luther & C. Knupp (2003) Structural evidence for the interaction of C-protein (MyBP-C) with actin and sequence identification of a possible actin-binding domain. J. Mol. Biol. 331:713-724.
P.K. Luther, R. Padron, S. Ritter, R. Craig and J.M. Squire (2003) Heterogeneity of Z-band structure within a single muscle sarcomere. J. Mol. Biol. 332:161-169. (Journal Cover)
Joya, J.E., Kee, A.J., Nair-Shalliker, V., Ghoddusi, M., Nguyen, M-A.T., Luther, P. & Hardeman, E.C. (2004) Muscle weakness in a mouse model of nemaline myopathy can be reversed with exercise and reveals a novel myofiber repair mechanism. Human Mol. Gen. 13:2633-2645.
Squire, J.M., Al-Khayat, H.A., Knupp, C., Luther, P.K. (2005) Molecular architecture in muscle contractile assemblies. Adv Protein Chem, 71:17-87.
Burgoyne T, Muhamad F, Luther PK. (2008) Visualization of cardiac muscle thin filaments and measurement of their lengths by electron tomography. Cardiovasc Res. 77:707-712.
Bödvarsson, B., S. Klim, M. Mørkebjerg, S. Mortensen, C.H. Yoon, J. Chen, J.R. Maclaren, P.K. Luther, J.M. Squire, P.J. Bones, and R.P. Millane. (2008) A morphological image processing method for locating myosin filaments in muscle electron micrographs. Image and Vision Computing. 26:1073-1080.
Luther, P.K., P.M. Bennett, C. Knupp, R. Craig, R. Padron, S.P. Harris, J. Patel, and R.L. Moss. (2008) Understanding the organisation and role of myosin binding protein C in normal striated muscle by comparison with MyBP-C knockout cardiac muscle. J Mol Biol. 384:60-72..
Yoon, C.H., B. Bodvarsson, S. Klim, M. Morkebjerg, S. Mortensen, J. Chen, J.R. Maclaren, P.K. Luther, J.M. Squire, P.J. Bones, and R.P. Millane. (2009) Determination of myosin filament orientations in electron micrographs of muscle cross sections. IEEE Trans Image Process. 18:831-9.
Luther, P.K. (2009) The vertebrate muscle Z-disc: sarcomere anchor for structure and signalling. J Muscle Res Cell Motil. 115:275-282.
Bhavsar, P.K., N.J. Brand, L.E. Felkin, P.K. Luther, M.E. Cullen, M.H. Yacoub, and P.J. Barton. (2010) Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and fibroblast-derived IGF-1. J Cardiovasc Transl Res. 3:688-95.
Luther, P.K. and Vydyanath, A. (2011) Myosin binding protein-C: An essential protein in skeletal and cardiac muscle. J. Muscle Res Cell Motility. 31:303-305.
Machuca-Tzili,L.E., Thorpe, A., Timson, C.M., Wigmore, P., Luther, P.K. and Brook, D. (2011) Deficiency of Muscleblind-like 2 Causes Myotonic Dystrophy Splicing Alterations and Developmental Abnormalities in Zebrafish Embryos. Disease Models and Mechanisms. Doi:10.1242/dmm.004150
Book Chapters and Reviews
Luther, P.K. (1992) "Section shrinkage and radiation damage" in "Electron Tomography" (ed. J. Frank) Plenum, New York, 39-60.
Luther, P.K. Munro, P.M.G. & Squire, J.M. (1995) Muscle ultrastructure in the teleost fish. Micron, 26, 431-459.
Luther, P.K. (2001) Section shrinkage: Impact for routine and 3D electron microscopy, Microscopy and Analysis, 7-9.
Luther, P.K. (2004) Evolution of the Muscle Lattice in the Vertebrate Kingdom, Microscopy and Analysis, March
Luther, P.K. (2007) Structural analysis of cardiac muscle by modern electron microscopy. British Society for Cardiovascular Research Bulletin, 20:4-10.
Luther, P.K. (2007) Sample shrinkage and radiation damage of plastic sections, in “Electron Tomography, Second Edition” (ed. J. Frank) Springer, New York, 17-48.
Squire, J.M., C. Knupp, and P.K. Luther. 2008. Zebrafish--topical, transparent, and tractable for ultrastructural studies. J Gen Physiol. 131:439-43.